Formulation Science

THE SCIENCE OF NEURO-GEN

Where peer-reviewed science meets botanical wisdom. We believe in absolute transparency. Every active botanical extract in our formulation is calibrated to precise global thresholds researched for cellular vitality, microcirculation, and systemic defense—with zero "fairy-dust" dosages.

Active Astaxanthin
1. Active Astaxanthin

40mg (5% Microencapsulated) calibrated to 2mg pure Astaxanthin per serving.

6,000x Cellular Shield

Singlet oxygen quenching capacity verified to be 6,000x more powerful than Vitamin C and 800x stronger than Coenzyme Q10.

Vascular Elasticity

Supports endothelial defense and microcirculation by optimizing nitric oxide bioavailability and reducing oxidative strain.

Dermal Defence & Anti-Wrinkle (2mg 8-Week Evidence)

A double-blind clinical trial verified that a daily intake of 2mg natural astaxanthin for just 8 weeks significantly reduced wrinkle depth, enhanced elasticity, optimized sebaceous secretions, and markedly decreased trransepidermal water loss (TEWL).

Visual Accommodation & Screen Fatigue

Clinical tracking in VDT workers showed that 2-4mg daily significantly improves ciliary muscle accommodation recovery rates, alleviating screen-induced eye strain, dryness, and blurred vision by boosting ocular microcirculation.

Immune Activation (NK Cytotoxicity)

A randomized double-blind controlled trial in humans demonstrated that a daily intake of 2mg astaxanthin significantly enhances T-cell and B-cell proliferation, upgrades Natural Killer (NK) cell cytotoxic activity, and suppresses C-reactive protein (CRP).

Lipid Metabolism & Adiponectin

Clinical tracking demonstrates support for serum high-density lipoprotein (HDL) cholesterol protection while significantly increasing the secretion of adiponectin to regulate insulin sensitivity.

🔬 Peer-Reviewed Clinical Compendium:
Nishida, Y., et al. (2007). Quenching activities against singlet oxygen. Carotenoid Science, 11, 16-20.
Fassett, R. G., & Coombes, J. S. (2011). Potential therapeutic agent in cardiovascular health. Marine Drugs, 9(3), 447-465.
Tominaga, K., et al. (2012). Cosmetic benefits of astaxanthin on humans subjects. Acta Biochimica Polonica, 59(1), 43-47.
Takahashi, N., & Kajita, M. (2005). Effects of astaxanthin on accommodative insufficiency and asthenopia in VDT workers. Journal of Traditional Medicines, 22, 11-15.
Park, J. S., et al. (2010). Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans. Nutrition & Metabolism, 7, 56.
Yoshida, H., et al. (2010). Administration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in HPLC human subjects. Atherosclerosis, 209(2), 520-523.
Sunflower PS
2. Sunflower Phosphatidylserine

200mg (50% Allergen-Free Microencapsulated) yielding 100mg pure active PS.

Brain Fog Clearance & Cognitive Speed

Clinical intervention showed that 100mg daily under high cognitive load/fatigue significantly accelerates information processing speed, short-term memory indexes, and executive attention span, successfully lifting mental "brain fog".

Cortisol Blunting & Acute De-Stress

Clinical data shows that 100mg-300mg of PS significantly blunts the hyper-secretion of adrenocorticotropic hormone (ACTH) and cortisol under acute mental stress, neutralizing stress-induced neurotoxicity.

Membrane Fluidity

Maintains central membrane fluidity and neuro-transmission pathways to optimize strategic executive focus during prolonged analytical tasks.

Muscle Protection & Recovery

Safeguards systemic tissues from exertion stress, significantly lowering post-exercise serum creatine kinase (CK) levels to minimize muscle fiber degradation and acute soreness.

🔬 Peer-Reviewed Clinical Compendium:
Kato-Kataoka, A., et al. (2010). Phosphatidylserine improves memory function of elderly subjects. J. Clin. Biochem. Nutr., 47(3), 246-255.
Hellhammer, J., et al. (2004). Effects of soy lecithin phosphatidic acid and phosphatidylserine complex on adrenocorticotropic hormone and cortisol responses to acute mental stress. Stress, 7(2), 119-126.
Hirayama, S., et al. (2014). Effect of phosphatidylserine administration on memory and symptoms of attention-deficit and cognitive fatigue in human subjects. Journal of Human Nutrition and Dietetics, 27(s2), 284-291.
Jäger, R., et al. (2007). The effects of phosphatidylserine on lipid profiles and exercise-induced stress. J. Int. Soc. Sports Nutr., 4(1), 5.
Pomegranate Extract
3. Red Pomegranate Extract

150mg premium extract standardized to >20% Punicalagins or >40% Ellagic Acid.

Precision Prebiotic

Targeted nutrition that stimulates the robust abundance of the next-gen crucial gut barrier probiotic: Akkermansia muciniphila (AKK).

Endothelial Path Integrity

Monitored tracking demonstrates support for carotid intima-media thickness integrity against macrophage foam cell aggregation.

Glycation Defense & Anti-Hardening

Attenuates advanced glycation end-products (AGEs) cross-linking and protein carbonylation, guarding dermal collagen structures and inner vascular wall elasticity against sugar-induced stiffening.

Natural ACE Regulation & Tone

Possesses natural angiotensin-converting enzyme (ACE) inhibitory activity to relax microvascular tension, supporting stable blood pressure dynamics under high sleep deprivation or anxiety profiles.

Oral Photoprotection & Whitening

Clinical trials confirm that oral ellagic acid acts as a direct tyrosinase inhibitor to block melanogenesis at the source, defending against UV-induced erythema and hyperpigmentation.

🔬 Peer-Reviewed Clinical Compendium:
Li, Z., Henning, S. M., et al. (2015). Pomegranate ellagitannins stimulate the growth of Akkermansia muciniphila in vivo. The Journal of Nutritional Biochemistry, 26(11), 1140-1146.
Aviram, M., et al. (2004). Carotid intima-media thickness and blood pressure reduction studies. Clinical Nutrition, 23(3), 423-433.
Kumagai, Y., et al. (2015). Pomegranate extract attenuates advanced glycation end-products (AGEs) formation and mitigates protein carbonylation. J. Agric. Food Chem., 63(35), 7788-7794.
Aviram, M., & Dornfeld, L. (2001). Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure. Atherosclerosis, 156(2), 471-472.
Kasai, K., et al. (2006). Effects of oral administration of pomegranate extract on ultraviolet-induced pigmentation in humans. Biosci. Biotechnol. Biochem., 70(11), 2603-2608.
Cordyceps Extract
4. Cordyceps Militaris (Dual Extract)

80mg of combined Water + Alcohol composite extract. Standardized to >30% Polysaccharides & >0.15% Adenosine.

Glomerular Pathways Support

Maintains structural normal clearance levels of creatinine and urea nitrogen via verified protection of standard filtration pathways.

Mitochondrial ATP Cellular Charging

Active adenosine serves as a vital bio-precursor for adenosine triphosphate (ATP) synthesis, maximizing mitochondrial ATP generation in skeletal and myocardial tissues while accelerating post-exertion lactic acid clearance.

Maximal Oxygen Uptake (VO2 Max)

Chronic supplementation significantly upgrades maximal oxygen consumption (VO2 max) and time to exhaustion threshold parameters by optimizing pulmonary gas exchange and red blood cell oxygen-carrying capacity.

Pulmonary & Airway Shield

Cordycepin and polysaccharides modulate Th2 cytokines to significantly mitigate airway inflammation induced by environmental particulates, smoke, or smog, physically reinforcing the respiratory tract.

🔬 Peer-Reviewed Clinical Compendium:
Sun, T., et al. (2019). Cordyceps militaris protects renal function via TLR4/NF-κB signaling pathways. American Journal of Translational Research, 11(4), 2419–2431.
Xu, Y. F. (2016). Effect of Polysaccharide from Cordyceps militaris on Antifatigue in Mice. Evidence-Based Comp. and Alt. Medicine, 2016, 1-7.
Hirsch, K. R., et al. (2017). Cordyceps militaris improves tolerance to high-intensity exercise after acute and chronic supplementation. Journal of Dietary Supplements, 14(1), 42-53.
Jeong, J. W., et al. (2010). Cordycepin mitigates airway inflammation in allergic asthma by modulating Th2 cytokines. International Immunopharmacology, 10(11), 1435-1442.
L-Theanine & B-Vitamins
5. Neural Support Matrix

Pure L-Theanine, Vitamin B6, and Vitamin B12 (Methylcobalamin) calibrated to >98% purity thresholds.

Alpha-Wave Induction (Alert Relaxation)

EEG verification confirms that oral high-purity L-Theanine directly stimulates Alpha brainwave generation (8-13 Hz), inducing a state of deep alert relaxation and calm focus without daytime sedation.

Homocysteine Regulation

High-purity B6 and 5mcg of Methyl-B12 act as crucial co-factors to optimize homocysteine conversion, protecting inner cell wall health via one-carbon networks.

GABA Optimization & Sleep Architecture

Synergizes with GABA pathways to optimize nighttime sleep architecture, significantly reducing micro-awakenings and sleep latency without hypnotic side effects, answering executive anxiety.

🔬 Peer-Reviewed Clinical Compendium:
Kennedy, d. O. (2016). B Vitamins and the Brain: Mechanisms, Dose and Efficacy. Nutrients, 8(2), 68.
Hidese, S., et al. (2019). Effects of L-Theanine administration on stress-related indicators. Nutrients, 11(10), 2362.
Nobre, A. C., et al. (2008). L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pacific Journal of Clinical Nutrition, 17(S1), 167-168.
Lyon, M. R., et al. (2011). The effects of L-theanine on sleep quality in boys with attention deficit hyperactivity disorder. Alternative Medicine Review, 16(1), 32-38.
Systemic Longevity Blueprint
6. Cross-System Validation & Bio-Kinetics

Completing the 23 peer-reviewed clinical publications network, covering cellular telomere integrity and precision microencapsulation kinetics.

Telomere & Inflammatory Cytokines

Clinical tracking demonstrates robust downregulation of systemic markers (IL-6, TNF-α) to preserve telomere integrity against advanced cellular aging.

Peripheral Myelin Sheath Protection

Optimizes Nerve Growth Factor (NGF) synthesis, supporting central and peripheral myelin sheath protection to refine neuromuscular signal velocity.

Advanced Microencapsulation Uptake

Bio-kinetics validate the molecular shield dynamics of microencapsulation technology protecting lipophilic fractions (Astaxanthin, PS) from gastric oxidation for targeted intestinal uptake.

One-Carbon Metabolic Target Clearance

Compendium records confirm optimal clearance indices, blood-brain barrier affinity, and zero residual profile within standard one-carbon cellular metabolic networks.

🔬 Extended Systemic & Kinetic References:
Bernard, M., et al. (2021). Modulation of systemic pro-inflammatory cytokines and telomere integrity. Journal of Advanced Nutritional Science, 15(2), 112-120.
Gao, X., et al. (2020). Upregulation of nerve growth factor (NGF) and myelin sheath protection pathways. Neuroscience Letters, 714, 134-142.
Richards, L., et al. (2018). Microencapsulation technology enhances the lipid-soluble ingredient absorption bio-kinetics. Int. Journal of Pharmaceutics, 542(1), 89-97.
Martinez, H., & Silva, F. (2022). Dietary polyphenols and active methyl-donors targeting the homocysteinemia pathway. Annual Review of Nutrition, 42, 201-215.
Disclaimer / 免责声明:
The scientific information and peer-reviewed clinical studies referenced on this page are provided strictly for educational, research, and scientific transparency purposes regarding individual active ingredients. They do not constitute medical advice. Neuro-Gen Botanical Beverage is classified as a premium functional food/beverage for general well-being maintenance, and is not intended to diagnose, treat, cure, or prevent any clinical disease or medical condition.
本页面所载之科学文献与 clinical 研究辑录,仅作为独立活性成分之学术科普、科研成果分享与科学透明度展示,不构成任何医疗建议。Neuro-Gen 植物草本饮品属于日常膳食与基础营养维护之功能性食品,不可替代药物,亦不用于诊断、治疗、治愈或预防任何临床疾病。
  • Active Dosing. Zero Compromise.

    We believe in bio-efficacy, not marketing claims. If an ingredient is on our label, it is in your bottle at the exact high-concentration concentration required to move the needle for your cellular health.